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- Tuesday, July 9, 2019 Study identifies new potential therapeutic target in lung cancer Source: Xinhua| 2019-07-08 23:18:14|Editor: Mu Xuequan BEIJING, July 8 (Xinhua) — Chinese researchers have identified a key gene with therapeutic potential in a type of lung cancer. MMP11, a tumor biomarker, has long been found to be associated with tumor progression in certain types of cancer, including breast, liver and colon. In the new study, researchers from Hefei Institutes of Physical Science under Chinese Academy of Sciences tried to decide its role in lung adenocarcinoma (LUAD), the most common type of lung cancer. The researchers first performed gene expression profiling on datasets of LUAD patients, and found the expression of MMP11 increased in both tumor tissues and sera from LUAD patients. Further studies showed that MMP11 played a key role in promoting the proliferation, migration and invasion of tumor cells. They then used anti-MMP11 antibody to treat human LUAD cell lines, and the growth and migration of cancer cells were significantly slowed. In animal studies, administration of anti-MMP11 antibody at a a dose of 1 microgram per gram body weight could significantly suppress tumor growth with mice transplanted with human LUAD tissues. Driver genes refer to genes that help a malignant cancer to form and grow. The researchers said the study indicated that MMP11 was a potential driver gene associated with LUAD and holds potential to be a target for treating lung cancer. The researchers reported their findings in the U.S. journal Molecular Therapy-Oncolytics.
- Study identifies new potential therapeutic target in lung cancer
- MAJORITY OF CHINESE TEENS ARE NOW NEAR SIGHTED.
- The U.S. Border Patrol was disinvited from a job fair at a local college in San Jose, California
- Possibly the most dangerous flashpoint today
- Follow Fr. Orthohippo on WordPress.com
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Monthly Archives: February 2011
HUGE LAW ENFORCEMENT FATALITIES?
It is far too early to draw any conclusions from these statistics. It is soon enough to begin to pay attention to the trends developing, however. In less than two full months (January & most of February 2011) law enforcement … Continue reading
Senate Democrats Stonewalling on Power Grid Collapse? Why?
Here is an article which I believe as many people as possible should read. It highlights a strange situation in congress. The actions of both the white house ( a special commission in favor) and house of representatives (unanimously in … Continue reading
A LETTER FROM THE GRAVE
Here is a letter from the grave. It has generated little notice among North American news sources. It has received only small attection among many Christian news sources. It is worth reading. You may have to write such a letter … Continue reading
Posted in abuse, evil, prejudice, Uncategorized
Tagged christian persecution, prejudice, spiritual abuse, Uncategorized
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KNOW YOUR “COMPETITION”
Very few Christians really know what Islam is about. In fact, like most Christians concerning their own faith, most Muslims have only a limited understanding about their own branches of Islam. The zealots among both faiths know a great deal … Continue reading
Posted in cultural blinders, culture differences, faith, history, politics, prejudice, Uncategorized
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TENSION BETWEEN GRACE AND WORKS
One of our long standing tensions among Christians is the relationship between our deeds and God’s grace. Historically, different understandings on this subject within Christianity have spawned a number of new traditions within the Christian family. These traditions (Holiness, Calvinist, … Continue reading
Posted in history, spirituality, theology, Uncategorized
Tagged spirituality, theology, Uncategorized
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PIRATES BEWARE! THE US NAVY NOW HAS WHAT IT NEEDS
This is the LCS-2 at sea trials, running at 45 knots while at half power in this turn. It holds many helicopters, and is a perfect platform for, among other things, engaging pirates. The navy plans 55 of this new … Continue reading
Washington at Work Once Again
Mandatory Arabic language and culture classes for your school? Our Federal Goverement has a program for just this. It came as a complete surprise to the parents in this school system. The scope of our government’s plans for social engineering … Continue reading
Posted in authority, politics, Uncategorized
Tagged authority, politics, Uncategorized
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Here are a few signs, mostly from the China – Shanghai area. They are only part of those gathered by The Huffington Post. You never know what you will see when you travel. Shake your head or simply enjoy. Cityscapes … Continue reading
MORE BLIZZARD NEWS – A WEIRD VIEW
And you thought you had a weird auto crash? It holds nothing compared to this. F. Orthohippo Salem, New Hampshire – There are plenty of images of car crashes during the Snowstorm of 2011 but none quite like this. An … Continue reading
BLIZZARD NEWS
What is a blizzard? Blizzards are dangerous winter storms that are a combination of blowing snow and wind resulting in very low visibilities. While heavy snowfalls and severe cold often accompany blizzards, they are not required. Sometimes strong winds pick … Continue reading