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- Tuesday, July 9, 2019 Study identifies new potential therapeutic target in lung cancer Source: Xinhua| 2019-07-08 23:18:14|Editor: Mu Xuequan BEIJING, July 8 (Xinhua) — Chinese researchers have identified a key gene with therapeutic potential in a type of lung cancer. MMP11, a tumor biomarker, has long been found to be associated with tumor progression in certain types of cancer, including breast, liver and colon. In the new study, researchers from Hefei Institutes of Physical Science under Chinese Academy of Sciences tried to decide its role in lung adenocarcinoma (LUAD), the most common type of lung cancer. The researchers first performed gene expression profiling on datasets of LUAD patients, and found the expression of MMP11 increased in both tumor tissues and sera from LUAD patients. Further studies showed that MMP11 played a key role in promoting the proliferation, migration and invasion of tumor cells. They then used anti-MMP11 antibody to treat human LUAD cell lines, and the growth and migration of cancer cells were significantly slowed. In animal studies, administration of anti-MMP11 antibody at a a dose of 1 microgram per gram body weight could significantly suppress tumor growth with mice transplanted with human LUAD tissues. Driver genes refer to genes that help a malignant cancer to form and grow. The researchers said the study indicated that MMP11 was a potential driver gene associated with LUAD and holds potential to be a target for treating lung cancer. The researchers reported their findings in the U.S. journal Molecular Therapy-Oncolytics.
- Study identifies new potential therapeutic target in lung cancer
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Category Archives: India
Possibly the most dangerous flashpoint today
India launches air strike inside Pakistan; Islamabad denies militant camp hit By Abu Arqam Naqash and Sanjeev Miglani , Reuters•February 26, 2019 India launches air strike inside Pakistan; Islamabad denies militant camp hit More By Abu Arqam Naqash and Sanjeev … Continue reading
Posted in fence controls, foreign policies, India, Uncategorized, WAR
Tagged Pakistan military
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What? Petrol pumps in eight states to be shut on Sundays from May 14. Ouch!
Beginning May 14, fuel outlets in eight states & UTs will remain shut every Sunday on account of PM Modi’s call to conserve oil, a fuel pump owners’ agency said on Tuesday. The states/UTs are TN, Kerala, Karnataka, Puducherry, Andhra, … Continue reading
Eunuch stripped before them and refused to get dressed unless they paid up
ws Home » City » Mumbai TNN | Sep 1, 2016, 11.43 PM IST http://timesofindia.indiatimes.com/city/mumbai/Eunuch-strips-in-local-does-not-budge-till-young-couple-pays-up/articleshow/53969414.cms Mumbai: A young couple, new to travelling by trains, underwent a horrific ordeal on a Harbour local recently when a eunuch stripped before them and … Continue reading
Posted in India, Uncategorized
Tagged blackmail, difficult train ride, eunuch, female eunuchs
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Attack on low-caste men sparks protests
Attack on low-caste men sparks protests AAP 10:53PM July 20, 2016 Protesters from India’s low-caste community have blocked roads and attacked government buses in Prime Minister Narendra Modi’s home state in a third day of demonstrations over the flogging of … Continue reading
Posted in freedoms lost, India, India caste problem, Uncategorized
Tagged caste attacks, caste prejudice
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India’s third-gender ‘hijra’ community balances acceptance with religious identity
Yasmine Canga-Valles and Olivia Lace-Evans | July 14, 2015 | Leave a Comment 5 3reddit0 0 AHMEDABAD, India (RNS) Tucked away in the Gomtipur ghetto sits the dusty pink home of Shobha, Shilpa and Joya, members of Ahmedabad’s small hijra community. … Continue reading
Posted in Hajits, India, third sex gender, transgender
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