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- Tuesday, July 9, 2019 Study identifies new potential therapeutic target in lung cancer Source: Xinhua| 2019-07-08 23:18:14|Editor: Mu Xuequan BEIJING, July 8 (Xinhua) — Chinese researchers have identified a key gene with therapeutic potential in a type of lung cancer. MMP11, a tumor biomarker, has long been found to be associated with tumor progression in certain types of cancer, including breast, liver and colon. In the new study, researchers from Hefei Institutes of Physical Science under Chinese Academy of Sciences tried to decide its role in lung adenocarcinoma (LUAD), the most common type of lung cancer. The researchers first performed gene expression profiling on datasets of LUAD patients, and found the expression of MMP11 increased in both tumor tissues and sera from LUAD patients. Further studies showed that MMP11 played a key role in promoting the proliferation, migration and invasion of tumor cells. They then used anti-MMP11 antibody to treat human LUAD cell lines, and the growth and migration of cancer cells were significantly slowed. In animal studies, administration of anti-MMP11 antibody at a a dose of 1 microgram per gram body weight could significantly suppress tumor growth with mice transplanted with human LUAD tissues. Driver genes refer to genes that help a malignant cancer to form and grow. The researchers said the study indicated that MMP11 was a potential driver gene associated with LUAD and holds potential to be a target for treating lung cancer. The researchers reported their findings in the U.S. journal Molecular Therapy-Oncolytics.
- Study identifies new potential therapeutic target in lung cancer
- MAJORITY OF CHINESE TEENS ARE NOW NEAR SIGHTED.
- The U.S. Border Patrol was disinvited from a job fair at a local college in San Jose, California
- Possibly the most dangerous flashpoint today
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Category Archives: musings
‘Weeping’ Mary Statue in Israel. I’d go see this myself. You never know.
Hundreds Flock to ‘Weeping’ Mary Statue in Israel February 12, 2014 2 Comments Yahoo news: Hundreds of people have flocked to a small town in northern Israel to view a statue of the Virgin Mary that residents say “weeps” oil. Members … Continue reading
Posted in christian, doubts, Israel, musings, Uncategorized
Tagged christian, fun, Israel, Uncategorized, weeping religious statues
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HOW DID YOU GROW UP? GROWING CULTURAL BLINDERS
START OF A JOURNEY – A number of folks have asked me to reprint how I grew up, and what that meant today. So, here it is, edited, I hope, to be helpful. Everyone the world over develops prejudices and … Continue reading
HOW MANY DAYS DO YOU HAVE BURNED INTO YOUR MEMORY?
Do you remember anything specific that happened in your first grade class? I can bring to mind two such incidents. The first one happened in the winter. I learned the hard way not to put my tongue on the metal … Continue reading
WHERE DO ALL THE REALLY AVENTUROUS GO?
Fr. Ernesto, aka Fr. Orthoduck when he is less serious, has written an interesting speculation based on history and musings. It well could be as he describes below. You can find his blog, mostly serious inquiry into theology, orthodox history, … Continue reading
Posted in culture differences, history, musings, Uncategorized
Tagged cultural views, Uncategorized
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A DRAGON LIVES FOREVER, BUT NOT SO LITTLE BOYS
Some thoughts on idealism, parenting, and being grandparents. Judy and I were not of the baby boomer generation. We got to watch babyboomers develop and fade away to those next “generations”. We were of the “beat” generation, sympathizers with Jack … Continue reading
SOME GENERATIONAL DIFFERENCES
This cartoon identifies several major generational differences present in our society today. At the same time it captures the essence of a major component of our war effort in WWII and to this day. Fr. Ernesto’s post on OrthoCuban includes … Continue reading