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- Tuesday, July 9, 2019 Study identifies new potential therapeutic target in lung cancer Source: Xinhua| 2019-07-08 23:18:14|Editor: Mu Xuequan BEIJING, July 8 (Xinhua) — Chinese researchers have identified a key gene with therapeutic potential in a type of lung cancer. MMP11, a tumor biomarker, has long been found to be associated with tumor progression in certain types of cancer, including breast, liver and colon. In the new study, researchers from Hefei Institutes of Physical Science under Chinese Academy of Sciences tried to decide its role in lung adenocarcinoma (LUAD), the most common type of lung cancer. The researchers first performed gene expression profiling on datasets of LUAD patients, and found the expression of MMP11 increased in both tumor tissues and sera from LUAD patients. Further studies showed that MMP11 played a key role in promoting the proliferation, migration and invasion of tumor cells. They then used anti-MMP11 antibody to treat human LUAD cell lines, and the growth and migration of cancer cells were significantly slowed. In animal studies, administration of anti-MMP11 antibody at a a dose of 1 microgram per gram body weight could significantly suppress tumor growth with mice transplanted with human LUAD tissues. Driver genes refer to genes that help a malignant cancer to form and grow. The researchers said the study indicated that MMP11 was a potential driver gene associated with LUAD and holds potential to be a target for treating lung cancer. The researchers reported their findings in the U.S. journal Molecular Therapy-Oncolytics.
- Study identifies new potential therapeutic target in lung cancer
- MAJORITY OF CHINESE TEENS ARE NOW NEAR SIGHTED.
- The U.S. Border Patrol was disinvited from a job fair at a local college in San Jose, California
- Possibly the most dangerous flashpoint today
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Category Archives: history
Russian claims of political territorial Oversight of Ukrainian state drastically challenged.
Ukrainian Orthodox Church breaks away from Russian influence ISTANBUL (AP) — An independent Ukrainian Orthodox church was created at a signing ceremony in Turkey on Saturday, formalizing a split with the Russian church it had been tied to since 1686. … Continue reading
USA CHANGING SPEECH PATTERNS
Recently I was shocked to discover that I was observing and ignoring a major shift in American speech patterns. For some reason, I had decided it was just a part of “Young folks” speech. Woops! This August I was in … Continue reading
Citrus enters our Mediterranean lives
January 2018 Vol. VI, No. 1 When Life Gives You Lemons: Tracking the Earliest Citrus in the Mediterranean By Dafna Langgut Jaffa orange poster One of the most famous Levantine exports of the 20th century was the Jaffa orange, and … Continue reading
Posted in archaeology, history, Personal, science, Uncategorized
Tagged citrus in our lives
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HOW TO CHANGE HISTORY : USA’ s CIVIL WAR CHANGE BY SOUTHERN HISTORIANS
Jane Dailey, Contributor Associate Professor of History, University of Chicago The Confederate General Who Was Erased There’s a reason you won’t find many monuments in the South to one of Robert E. Lee’s most able deputies. Historical via Getty Images … Continue reading
A Very Rare Way to Commit Suicide
Demographic Suicide | George Weigel | First Things Ten years ago, after my meditation on Europe, The Cube and the Cathedral, had appeared in several languages, I was invited to speak to members of the European Parliament in Brussels. There, … Continue reading
Posted in church, cultural shifts, demographics, history, Uncategorized
Tagged National suicides, Personal, Uncategorized
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Time of Christ legal documents show women’s rights and place in society
By: Philip Esler Everyone has heard of the ancient Jewish religious scrolls discovered at Qumran by the Dead Sea in the middle of the 20th century. But who is aware that nearly 100 legal papyri have been found in the same … Continue reading
Posted in archaeology, history, Uncategorized
Tagged Women and law, women and time of christ
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ONCE A PRIEST, ALWAYS A PRIEST
CATHOLICWEBPHILOSOPHER Sunday, March 26, 2017 ONCE A PRIEST, ALWAYS A PRIEST A young man had a vocation to the priesthood, so his bishop sent him to study in Rome. After being duly ordained priest and serving in the diocese, his … Continue reading
Posted in authority, church, history, religious vocation, Uncategorized
Tagged Demitted priest, PRIESTHOOD, Uncategorized
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Guns and Academia – Very “Unexpected” and Surprising Results Here
According to a study in the Harvard Journal of Law & Public Policy, which cites the Centers for Disease Control, the U.S. National Academy of Sciences and the United Nations International Study on Firearms Regulation, the more guns a nation … Continue reading
Eastern Orthodox Cacophony in America
The American Interest mead cohen berger shevtsova garfinkle michta grygiel This is your free article this month. Published on: February 10, 2016 Religion & Other Curiosities Eastern Orthodox Cacophony in America Peter Berger In the American context, how can Orthodoxy … Continue reading
Posted in Eastern Orthodoxy, history, orthodox, Russia, Uncategorized, US
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Archives Show Vatican Tried to Stop Armenian Genocide
Monument to the Armenian genocide of 1894-96 and 1915-16, in Yerevan, Armenia. (Pietro Basilico/Dreamstime) Wednesday, 15 Apr 2015 10:15 AM By Aleteia.org VATICAN CITY — Why did Pope Francis’ controversial comments on Sunday about the “Armenian Genocide” cause such … Continue reading
Posted in catholic, history, Islam, persecution, Uncategorized
Tagged Armenian Genocide, genocide, Pope Francis, t, Turkish genocide, Vatican efforts to halt genocide
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