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- Tuesday, July 9, 2019 Study identifies new potential therapeutic target in lung cancer Source: Xinhua| 2019-07-08 23:18:14|Editor: Mu Xuequan BEIJING, July 8 (Xinhua) — Chinese researchers have identified a key gene with therapeutic potential in a type of lung cancer. MMP11, a tumor biomarker, has long been found to be associated with tumor progression in certain types of cancer, including breast, liver and colon. In the new study, researchers from Hefei Institutes of Physical Science under Chinese Academy of Sciences tried to decide its role in lung adenocarcinoma (LUAD), the most common type of lung cancer. The researchers first performed gene expression profiling on datasets of LUAD patients, and found the expression of MMP11 increased in both tumor tissues and sera from LUAD patients. Further studies showed that MMP11 played a key role in promoting the proliferation, migration and invasion of tumor cells. They then used anti-MMP11 antibody to treat human LUAD cell lines, and the growth and migration of cancer cells were significantly slowed. In animal studies, administration of anti-MMP11 antibody at a a dose of 1 microgram per gram body weight could significantly suppress tumor growth with mice transplanted with human LUAD tissues. Driver genes refer to genes that help a malignant cancer to form and grow. The researchers said the study indicated that MMP11 was a potential driver gene associated with LUAD and holds potential to be a target for treating lung cancer. The researchers reported their findings in the U.S. journal Molecular Therapy-Oncolytics.
- Study identifies new potential therapeutic target in lung cancer
- MAJORITY OF CHINESE TEENS ARE NOW NEAR SIGHTED.
- The U.S. Border Patrol was disinvited from a job fair at a local college in San Jose, California
- Possibly the most dangerous flashpoint today
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Monthly Archives: February 2016
Joint Declaration of Pope Francis and Patriarch Kirill
12/02/2016 22:19 Joint Declaration of Pope Francis and Patriarch Kirill of Moscow and All Russia “The grace of the Lord Jesus Christ and the love of God the Father and the fellowship of the holy Spirit be with all of … Continue reading
Eastern Orthodox Cacophony in America
The American Interest mead cohen berger shevtsova garfinkle michta grygiel This is your free article this month. Published on: February 10, 2016 Religion & Other Curiosities Eastern Orthodox Cacophony in America Peter Berger In the American context, how can Orthodoxy … Continue reading
Posted in Eastern Orthodoxy, history, orthodox, Russia, Uncategorized, US
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100 US Anglican parishes convert to Roman Catholic Church
Saturday 06 February 2016 100 US Anglican parishes convert to Roman Catholic Church About 100 traditionalist Anglican parishes across the United States have decided to convert en masse to the Roman Catholic Church, it emerged yesterday Pope Benedict XVI – … Continue reading
Australia not denying it paid people smugglers
The boat at the centre of the payment allegations, which was reportedly carrying predominantly Sri Lankan nationals, was intercepted late in May last year. The captain told a court in Indonesia that he negotiated payment with officials to take the … Continue reading
Lest you think el nino effects just you……..
El Nino has intensified dry spell: Met Dept. [Sri Lanka weather (formerly Ceylon) Indian Ocean Southeast of India] 2016-02-05 03:33:38 The current dry spell experienced in the country is a result of the EL Nino phenomenon, the Department of … Continue reading
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British scientists granted permission to genetically modify human embryos
Home» News» Science» Science News British scientists granted permission to genetically modify human embryos The Francis Crick institute will genetically edit the leftover embryos from from IVF clinics 3K 4 22 3K Email Scientists will genetically edit human embryos to … Continue reading
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