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- Tuesday, July 9, 2019 Study identifies new potential therapeutic target in lung cancer Source: Xinhua| 2019-07-08 23:18:14|Editor: Mu Xuequan BEIJING, July 8 (Xinhua) — Chinese researchers have identified a key gene with therapeutic potential in a type of lung cancer. MMP11, a tumor biomarker, has long been found to be associated with tumor progression in certain types of cancer, including breast, liver and colon. In the new study, researchers from Hefei Institutes of Physical Science under Chinese Academy of Sciences tried to decide its role in lung adenocarcinoma (LUAD), the most common type of lung cancer. The researchers first performed gene expression profiling on datasets of LUAD patients, and found the expression of MMP11 increased in both tumor tissues and sera from LUAD patients. Further studies showed that MMP11 played a key role in promoting the proliferation, migration and invasion of tumor cells. They then used anti-MMP11 antibody to treat human LUAD cell lines, and the growth and migration of cancer cells were significantly slowed. In animal studies, administration of anti-MMP11 antibody at a a dose of 1 microgram per gram body weight could significantly suppress tumor growth with mice transplanted with human LUAD tissues. Driver genes refer to genes that help a malignant cancer to form and grow. The researchers said the study indicated that MMP11 was a potential driver gene associated with LUAD and holds potential to be a target for treating lung cancer. The researchers reported their findings in the U.S. journal Molecular Therapy-Oncolytics.
- Study identifies new potential therapeutic target in lung cancer
- MAJORITY OF CHINESE TEENS ARE NOW NEAR SIGHTED.
- The U.S. Border Patrol was disinvited from a job fair at a local college in San Jose, California
- Possibly the most dangerous flashpoint today
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Monthly Archives: May 2017
Ecumenical Patriarch to participate in celebrations for 500th anniversary of Protestant Reformation
Version:1.0 StartHTML:000000200 EndHTML:000014232 StartFragment:000011595 EndFragment:000014176 StartSelection:000011595 EndSelection:000014166 SourceURL:http://orthochristian.com/103857.html Ecumenical Patriarch to participate in celebrations for 500th anniversary of Protestant Reformation / OrthoChristian.Com Moscow, May 26, 2017 Photo: theorthodoxchurch.info During his visit to the Ecumenical Patriarchate in Constantinople in September 2016, … Continue reading
Posted in orthodox, Protestantism, Uncategorized
Tagged 500th anniversary Protestant Reformation
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A Very Rare Way to Commit Suicide
Demographic Suicide | George Weigel | First Things Ten years ago, after my meditation on Europe, The Cube and the Cathedral, had appeared in several languages, I was invited to speak to members of the European Parliament in Brussels. There, … Continue reading
Posted in church, cultural shifts, demographics, history, Uncategorized
Tagged National suicides, Personal, Uncategorized
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Time of Christ legal documents show women’s rights and place in society
By: Philip Esler Everyone has heard of the ancient Jewish religious scrolls discovered at Qumran by the Dead Sea in the middle of the 20th century. But who is aware that nearly 100 legal papyri have been found in the same … Continue reading
Posted in archaeology, history, Uncategorized
Tagged Women and law, women and time of christ
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20 New Science Papers Find Climate is Driven by Solar Changes
20 New Science Papers Find Climate is Driven by Solar Changes 20 New Science Papers Find Climate is Driven by Solar Changes Published on April 28, 2017 Written by Kenneth Richard Earlier this month, the first installment in … Continue reading
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